Mandela University provides a diverse range of undergraduate and postgraduate programs in a variety of disciplines, including:

• Business and Economic Sciences

1. Accounting
2. Business Management
3. Economics
4. Human Resource Management
5. Information Systems
6. Marketing Management
7. Tourism Management

• Education

1. Early Childhood Development
2. Foundation Phase Education
3. Intermediate Phase Education
4. Senior Phase and Further Education and Training Teaching
5. Education Leadership and Management
6. Inclusive Education

• Engineering, the Built Environment, and Technology

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1. Chemical Engineering
2. Civil Engineering
3. Computer Systems Engineering
4. Electrical Engineering
5. Electronic Engineering
6. Industrial Engineering
7. Information Technology
8. Mechanical Engineering
9. Mechatronics Engineering

• Health Sciences

1. Biomedical Technology
2. Dental Technology
3. Emergency Medical Care
4. Environmental Health
5. Medical Laboratory Science
6. Nursing
7. Occupational Therapy
8. Pharmacy
9. Physiotherapy
10. Radiography
11. Sport and Exercise Science

• Humanities

1. Anthropology and Development Studies
2. English
3. Geography
4. History
5. International Relations
6. Journalism, Media, and Philosophy
7. Languages and Literature
8. Music and Art
9. Political and Conflict Studies
10. Psychology
11. Public Management
12. Social Work
13. Sociology

• Law

1. LLB (Bachelor of Laws)
2. LLM (Master of Laws)

• Natural Sciences

1. Biochemistry and Microbiology
2. Botany and Zoology
3. Chemistry
4. Computer Science
5. Mathematics and Applied Mathematics
6. Physics
7. Statistics